Multiplex / Cytokine

Multiplex cytokine assays can play a crucial role in first-in-human clinical trials. They can assist researchers in understanding the impact of drug therapies and support the critical decision -making process in new drug development.

Hemostasis Reference Laboratory [HRL] is a specialized laboratory with a long history of assisting clients with study design and assay selection to help ensure the best possible outcomes.

Hrl Cytokine
Hrl Device

Multiplex Cytokine Assays

The simultaneous measurement of cytokines in a single sample provides increased throughput and reduced sample volume compared to traditional ELISA techniques. It is the ideal platform for measuring cytokines in a variety of matrices from human serum to tissue culture media.

HRL’s Meso Scale Discovery (MSD) multiplex platform:

The multiplex platform couples immunoassay methodology with electrochemiluminescence (ECL) detection to provide accurate and precise measurement of a multitude of different cytokine panels.

Analyzer 15

Advantages of the HRL MSD multiplex

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  • Accurately target low analyte levels in minimum sample volumes
  • Robust matrix tolerance including biological fluids (serum, urine, CSF ), tissue culture media, as well as complex biological matrices
  • 5-Log+ dynamic range: simultaneous comparison of pertinent cytokines, chemokines and other biomarkers in samples from diseased and normal patients at different intervals
  • Extensive menu of validated multiplex cytokine panels
  • Ability to add signature panels and develop custom assays

Laboratory Services

HRL offers multiplex cytokine analysis on the MESO QuickPlex SQ 120MM technology platform to address specific project application:

  • assay validation and analysis
  • consultation for study design
  • consultation to ensure proper sample collection and storage
  • technical and professional support for report and manuscript submissions

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